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DA-1241

SKU: orb3028725

Description

DA-1241 is a GPR119 agonist. By activating GPR119, it downregulates NFκB signaling, thereby inhibiting macrophage differentiation. Whether used alone or in combination with DPP4 inhibitors, DA-1241 can alleviate liver inflammation and restore the expression of liver genes linked to inflammation. It is applicable in the research of metabolic dysfunction-associated steatohepatitis (MASH).

Images & Validation

Key Properties

CAS Number1914136-10-9
MW471.543
FormulaC25H31F2N5O2
SMILESFC1=CC(OCCCC2CCN(C3=NC=C(C=N3)CC)CC2)=CC(F)=C1C4=NOC(=N4)C(C)C
TargetGPCR

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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DA-1241 (orb3028725)

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