Dalotuzumab Biosimilar (IGF1R / CD221 Reference Antibody）

SKU: orb2703822

Description

Dalotuzumab (MK-0646) is a recombinant humanized monoclonal antibody (IgG1 type) targeting IGF-1R. Dalotuzumab acts by inhibiting IGF-1- and IGF-2-mediated tumor cell proliferation, IGF-1R autophosphorylation, and Akt phosphorylation. Dalotuzumab also induces apoptosis and cycle arrest. Dalotuzumab in combination with other anticancer agents such as statins can enhance the antitumor activity of Dalotuzumab in vitro and in vivo.

Images & Validation

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Key Properties

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Antibody Type	Biosimilar Antibody
Clonality	Monoclonal
Target	Dalotuzumab Biosimilar（Anti-IGF1R / CD221 Reference Antibody）
Purity	>98%
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Disclaimer	For research use only

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Gene Symbol

Dalotuzumab Biosimilar（Anti-IGF1R / CD221 Reference Antibody）

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