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Danshenxinkun A

SKU: orb3023823

Description

Danshenxinkun A is a natural product isolated from Salvia miltiorrhiza (Tanshen) exhibiting neuraminidase inhibitory activity with an IC50 of 39.5 mg/L.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number65907-75-7
MW296.32
FormulaC18H16O4
SMILESCC(CO)C1=C(O)C(=O)c2c(ccc3c(C)cccc23)C1=O
TargetOthers,Cytochromes P450
SolubilityDMSO:≥ 80 mg/mL

Bioactivity

Target IC50
AGS cells:> 50 μM|Hep3B2 cells:> 50 μM
In Vitro
As a result, we identified 870 single peaks from total ion current and accurately identified 19 compounds from Danshen in this study. Further analysis showed that these compounds had three types of accumulation patterns and contents of most compounds had significant differences in samples from different planting areas. Network pharmacological analysis showed that Tanshinone IIA, Tanshinone IIB, Dehydromiltirone, Cryptotanshinone, Danshenxinkun A, Danshenxinkun B and Neocryptotanshinone might intervene thrombotic diseases by adjusting the targets mainly involved in pathways of endocrine system, signal transduction, signaling molecules and interaction, cell motility, environmental adaptation and nervous system.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Danshenxinkun A

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Protocol Information

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1 mg
$ 220.00
5 mg
$ 500.00
10 mg
$ 770.00
25 mg
$ 1,150.00
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