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DBCO-PEG4-Ahx-DM1

SKU: orb1473152

Description

DBCO-PEG4-Ahx-DM1 is a drug-linker conjugate composed of a potent microtubulin inhibitor DM1 and a linker DBCO-PEG4-Ahx to make antibody drug conjugate (ADC). Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery.

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Key Properties

CAS Number2479378-44-2
MW1297.92
Purity>95%
FormulaC68H89ClN6O17
SMILESCOC1=CC(C/C(C)=C/C=C/[C@@H](OC)[C@]2(O)NC(OC([C@@H](C)C(O3)[C@]3(C)[C@@H](OC([C@H](C)N(C)C(CCCCCNC(CCOCCOCCOCCOCCNC(CCC(N4CC(C=CC=C5)=C5C#CC6=C4C=CC=C6)=O)=O)=O)=O)=O)CC7=O)C2)=O)=CC(N7C)=C1Cl

Storage & Handling

DisclaimerFor research use only

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  • DBCO-PEG4-Ahx-DM1 [orb1988485]

    1297.92

    C68H89ClN6O17

    500 mg, 100 mg
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DBCO-PEG4-Ahx-DM1 (orb1473152)

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10 mg
$ 1,880.00
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