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DBCO-PEG4-Ahx-DM1

SKU: orb1988485

Description

DBCO-PEG4-Ahx-DM1 is a drug-linker conjugate that combines the microtubulin inhibitor DM1 (mertansine), an antibody-conjugatable maytansinoid designed to reduce systemic toxicity and improve tumor-specific delivery, with the linker DBCO-PEG4-Ahx, for developing antibody drug conjugates (ADCs).

Images & Validation

Key Properties

MW1297.92
FormulaC68H89ClN6O17
SMILESCOC1=CC(C/C(C)=C/C=C/[C@@H](OC)[C@]2(O)NC(OC([C@@H](C)C(O3)[C@]3(C)[C@@H](OC([C@H](C)N(C)C(CCCCCNC(CCOCCOCCOCCOCCNC(CCC(N4CC(C=CC=C5)=C5C#CC6=C4C=CC=C6)=O)=O)=O)=O)=O)CC7=O)C2)=O)=CC(N7C)=C1Cl
TargetDrug-Linker Conjugates for ADC

Storage & Handling

Storage-20°C
DisclaimerFor research use only

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  • DBCO-PEG4-Ahx-DM1 [orb1473152]

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    1297.92

    C68H89ClN6O17

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Protocol Information

DBCO-PEG4-Ahx-DM1 (orb1988485)

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