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Delta-Tocopherol

SKU: orb1301236

Description

Delta-Tocopherol, a Vitamin E isomer, exhibits antioxidant properties and is investigated as a potential skin-whitening agent with reduced dermal toxicity. Research applications include in vitro studies of melanogenesis inhibition and in vivo models for cosmetic efficacy and safety evaluation.

Research Area

Cell Biology, Metabolism Research

Images & Validation

Key Properties

CAS Number119-13-1
MW402.65
Purity99.14%
FormulaC27H46O2
SMILESCC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2cc(O)cc(C)c2O1
TargetEndogenous Metabolite,Apoptosis
SolubilityDMSO:125 mg/mL (310.44 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.93 mM)

Bioactivity

In Vitro
D-beta-tocopherol at 250 mug ml(-1) inhibited not only 28% of melanin synthesis in B16 cells, but also 34% of the tyrosinase activity, a very important cascade enzyme involved in the synthesis of melanin in melanoma cells. D-gamma-tocopherol also strongly inhibited up to 39% of melanin synthesis and 45% of the tyrosinase enzyme activity at the same concentration.

Storage & Handling

Storagestore at low temperature,keep away from direct sunlight | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Human Endogenous Metabolite, Inhibitor, inhibit, DeltaTocopherol, Delta-Tocopherol, Delta Tocopherol, Endogenous Metabolite, D-DELTA-TOCOPHEROL, EndogenousMetabolite, D-Δ-TOCOPHEROL, Δ-Tocopherol

Similar Products

  • Delta-Tocopherol (Standard) [orb3139523]

    119-13-1

    402.65

    C27H46O2

    50 mg
  • D-DELTA-TOCOPHEROL [orb1220652]

    >98% (HPLC)

    119-13-1

    402.7

    C27H46O2

    25 mg, 50 mg, 100 mg, 1 g, 500 mg, 200 mg
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Key Properties

No computed properties available.

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Protocol Information

Delta-Tocopherol (orb1301236)

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% DMSO +
%+
% Tween 80 +
%

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25 mg
$ 70.00
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