Depatuxizumab Antibody

SKU: orb2278701

Description

Depatuxizumab is a humanised monoclonal antibody targeting EGFR with blood-brain barrier (BBB) permeability, capable of inhibiting the growth of xenograft tumours expressing mutant EGFR vIII and wild-type EGFR. It can be conjugated with the ADC molecule Depatuxizumab mafodotin for the study of glioblastoma (GBM) and head and neck squamous cell carcinoma (SCCHN).

Images & Validation

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Key Properties

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Antibody Type	Inhibitor Antibody
Clonality	Recombinant
Target	EGFR
Purity	95.00%
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Concentration	5.88 mg/mL
Disclaimer	For research use only

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Gene Symbol

EGFR

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