Dexpramipexole dihydrochloride

SKU: orb1309770

Description

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	104632-27-1
MW	284.25
Purity	99.75%
Formula	C₁₀H₁₉Cl₂N₃S
SMILES	Cl.Cl.CCCNC1CCc2nc(N)sc2C1
Target	Dopamine Receptor
Solubility	10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (14.07 mM);DMSO:100 mg/mL (351.8 mM);H2O:100 mg/mL (351.8 mM)

Bioactivity

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In Vitro

Dextromethorphan has been found to have neur Protective effects and is being studied fo the treatment of amyotrophic lateral sclerosis (ALS). Dexpramipexole reduces mitochondrial Reactive oxygen species (ROS) production, inhibit the activation of apoptosis pathways, and improves cell survival in response to various neurotoxins and β-amyloid neurotoxicity. Compared wit the S-(-) isomer, dextromethorphan has lower dopamine agonist activity.

Storage & Handling

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Storage	store at low temperature \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Disclaimer	For research use only

Alternative Names

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R-(+)-Pramipexole dihydrochloride, Pramipexole Dihydrochloride, Pramipexole, R-Pramipexole, R-Pramipexole Dihydrochloride, Inhibitor, KNS 760704, KNS 760704 Dihydrochloride, KNS760704, KNS-760704, KNS760704 Dihydrochloride, KNS-760704 Dihydrochloride, KNS-760704 dihydrochloride, inhibit, (R)-Pramipexole dihydrochloride, (R)-Pramipexole, Dexpramipexole, Dexpramipexole dihydrochloride, Dexpramipexole Dihydrochloride, Dopamine Receptor, Dopamine, DopamineReceptor

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Compound Identifiers

PubChem CID

13670715 ↗

Key Properties

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No computed properties available.

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