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DFPQ

SKU: orb2564724

Description

DFPQ is a powerful and selective β-arrestin-biased negative allosteric modulator(NAM) targeting the β2-adrenergic receptor. It specifically inhibits the interaction of β-arrestin with β2AR without altering β-agonist-induced cAMP production. Additionally, DFPQ reduces functional desensitization of the β2AR in airway smooth muscle, enhancing β-agonists' capacity to maintain bronchorelaxation and curbing cell migration during prolonged β-agonist treatment.

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Key Properties

CAS Number911678-60-9
MW354.40
FormulaC20H20F2N4
SMILESFC1=CC=C(C=C1F)NC=2N=C3C=CC=CC3=C(N2)NC4CCCCC4

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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DFPQ (orb2564724)

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