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Dicentrine

SKU: orb1684647

Description

Dicentrine, the primary alkaloid from Ocotea puberula leaves, is an α1-adrenoceptor antagonist. Its activity, confirmed via [3H]prazosin binding and in vitro tension assays, supports research into benign prostatic hyperplasia (BPH) and related urological disorders.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number517-66-8
MW339.39
Purity99.99% (May vary between batches)
FormulaC20H21NO4
SMILESCN1[C@@]2(C=3C(C=4C(C2)=CC(OC)=C(OC)C4)=C5C(=CC3CC1)OCO5)[H]
TargetAdrenergic Receptor
SolubilityDMSO:8 mg/mL (23.57 mM)

Bioactivity

In Vitro
Dicentrine combined with TNF-α treatment at concentrations of 25, 30, and 40 μM significantly reduced the survival rate of A549 cells (54.85%, 54.35%, and 45.15%, respectively), demonstrating a more pronounced effect compared to Dicentrine alone .

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Dicentrine

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Key Properties

No computed properties available.

Protocol Information

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5 mg
$ 390.00
DispatchUsually dispatched within 5-10 working days
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