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Dichotomine C

SKU: orb3141859

Description

Dichotomine C ((R)-(-)-Dichotomine C) is a β-carboline alkaloid with anti-allergic properties. It inhibits the release of β-hexosaminidase from RBL-2H3 cells with an IC50 of 62 μM. Additionally, it suppresses antigen IgE-mediated release of TNF-α and IL-4 in RBL-2H3 cells, with IC50 values of 19 μM and 15 μM, respectively. This compound is applicable in the research of type I hypersensitivity reactions.

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Key Properties

CAS Number755036-45-4
MW286.28
FormulaC15H14N2O4
SMILES[C@@H](CO)(O)C1=C2C(C=3C(N2)=CC=CC3)=CC(C(OC)=O)=N1
TargetInterleukin,glycosidase,TNF

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Dichotomine C (orb3141859)

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