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DM4-SMCC

SKU: orb1988452

Description

DM4-SMCC is a non-cleavable drug-linker conjugate designed for constructing antibody-drug conjugates (ADCs). It delivers the potent antitubulin agent DM4 to target cells, demonstrating antitumor activity in both in vitro cytotoxicity assays and in vivo xenograft model studies.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1228105-52-9
MW1114.69
FormulaC54H72ClN5O16S
SMILESC[C@]12[C@@](O1)([C@H](C)[C@@]3(C[C@](O)([C@H](OC)/C=C/C=C(\C)/CC4=CC(N(C)C(=O)C[C@@H]2OC([C@@H](N(C(CCC(SC5C(=O)N(CC6CCC(C(ON7C(=O)CCC7=O)=O)CC6)C(=O)C5)(C)C)=O)C)C)=O)=C(Cl)C(OC)=C4)NC(=O)O3)[H])[H]
TargetDrug-Linker Conjugates for ADC,PROTAC Linker

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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  • DM4-SMCC [orb3033034]

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    1228105-52-9

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    C54H72CLN5O16S

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Key Properties

No computed properties available.

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Protocol Information

DM4-SMCC (orb1988452)

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Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

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