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DM4-SMCC

SKU: orb3033034

Description

​​DM4-SMCC​​ is an ​​antibody-drug conjugate (ADC) payload​​ that combines the potent ​​antitubulin agent DM4​​ with a ​​non-cleavable SMCC linker​​. This conjugate is designed to deliver cytotoxic effects specifically to tumor cells, leveraging DM4's ability to disrupt microtubule dynamics. The stable SMCC linker ensures controlled drug release, enhancing the ADC's ​​antitumor activity​​ while minimizing off-target toxicity.

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Key Properties

CAS Number1228105-52-9
MW1114.69139385223
Purity>98%
FormulaC54H72CLN5O16S
SMILESClC1C(=CC2CC(C)=CC=C[C@H]([C@]3(C[C@@H]([C@@H](C)[C@H]4[C@](C)([C@H](CC(N(C)C=1C=2)=O)OC([C@H](C)N(C)C(CCC(C)(C)SC1CC(N(C1=O)CC1CCC(C(=O)ON2C(CCC2=O)=O)CC1)=O)=O)=O)O4)OC(N3)=O)O)OC)OC |c:7,9|

Storage & Handling

DisclaimerFor research use only

Similar Products

  • DM4-SMCC [orb1988452]

    1228105-52-9

    1114.69

    C54H72ClN5O16S

    500 mg, 100 mg
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DM4-SMCC (orb3033034)

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100 mg
$ 2,740.00
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