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DNJ-20

SKU: orb3028107

Description

DNJ-20 is an α-glucosidase inhibitor with an IC50 of 55.3 μg/mL. It exhibits broad-spectrum activity against SARS-CoV-2. By interfering with the endoplasmic reticulum-associated glycoprotein folding process (ERQC), DNJ-20 hinders the proper processing of viral glycoproteins, thus blocking the formation and infection of viral particles. It is effective against several SARS-CoV-2 variants, as well as HCoV-229E and HCoV-0C43, with IC50 values reaching up to 1.49 μM. DNJ-20 can be utilized for pan-coronavirus research.

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Key Properties

CAS Number3081926-49-7
MW587.658
FormulaC31H41NO10
SMILESO(CCCCCCCCCCN1[C@H](CO)[C@@H](O)[C@H](O)[C@@H](O)C1)C2=C3C(OC(=CC3=O)C4=CC(O)=C(O)C=C4)=CC(O)=C2
TargetSARS-CoV,glycosidase

Storage & Handling

Storage-20°C
DisclaimerFor research use only

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DNJ-20 (orb3028107)

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