Dual Cathepsin L/JAK-IN-1

SKU: orb2945053

Description

DualCathepsinL/JAK-IN-1 (Compound A8) is a dual inhibitor of Cathepsin L and JAK kinases, demonstrating potent activity in vitro. It blocks key inflammatory pathways (MAPK, NF-κB, JAK/STAT) and shows research utility in models of acute lung injury (ALI) for investigating anti-inflammatory therapies.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Immunology & Inflammation, Protein Biochemistry, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

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Key Properties

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CAS Number	2450279-41-9
MW	351.833
Formula	C₁₉H₁₈ClN₅
SMILES	Cl.N1=CC=C(N=C1NC=2C=CC=C(N)C2)C3=CN(C=4C=CC=CC34)C
Target	p38 MAPK,Interleukin,JAK,Cysteine Protease,STAT

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

153529684 ↗

Key Properties

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No computed properties available.

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