Dusigitumab Antibody

SKU: orb1944150

Description

Dusigitumab (MEDI573) is a fully human monoclonal antibody targeting both IGF1 and IGF2. It inhibits IGF-1R phosphorylation with IC50 values of 0.97 µg/mL and 0.2 µg/mL against IGF1 and IGF2, respectively. This agent is utilized in cancer research, including in vitro cell signaling studies and in vivo xenograft models.

Research Area

Signal Transduction

Images & Validation

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Key Properties

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Antibody Type	Inhibitor Antibody
Clonality	Monoclonal
Target	IGF-1R
Molecular Weight	144.22 kDa
Purity	95.00% (May vary between batches)
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Concentration	5.55 mg/mL
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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IGF1R, MEDI573

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Quick Database Links

Gene Symbol

IGF-1R

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