(E)-3,4,5-Trimethoxycinnamic acid

SKU: orb1297136

Description

O-Methylsinapic acid, also known as (E)-3,4,5-Trimethoxycinnamic acid, is a natural compound isolated from Notopterygium incisum. It serves as a research standard and has been investigated in vitro for its potential anti-inflammatory and antioxidant properties in biochemical studies.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	20329-98-0
MW	238.24
Purity	99.83% (May vary between batches)
Formula	C₁₂H₁₄O₅
SMILES	O(C)C1=C(OC)C(OC)=CC(/C=C/C(O)=O)=C1
Target	5-HT Receptor,Others,GABA Receptor
Solubility	DMSO:60 mg/mL (251.85 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.39 mM)

Bioactivity

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Target IC50	5-HT2C receptor:2.5 μM\|5-HT2A receptor:>10 μM\|5-HT6 receptor:>10 μM\|5-HT7 receptor:>10 μM\|5-HT1A receptor:7.6 μM

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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antidepressant, anticonvulsant, anti-seizure, 5-hydroxytryptamine Receptor, 3,4,5-Trimethoxyphenylacrylic acid, 3,4,5-Trimethoxy-trans-cinnamic acid, 3,4,5-Trimethoxycinnamic acid, (E) 3,4,5 Trimethoxycinnamic acid, (E)3,4,5Trimethoxycinnamic acid, 5-HT Receptor, headache, epilepsy, GABA Receptor, Gamma-aminobutyric acid Receptor, O-Methylsinapic acid, Inhibitor, inhibit, TMCA, Polygalaceae, sedative, Serotonin, Serotonin Receptor, γ-Aminobutyric acid Receptor

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Compound Identifiers

PubChem CID

735755 ↗

Key Properties

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No computed properties available.

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