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(E)-AG 556

SKU: orb1306176

Description

AG 556 is a selective epidermal growth factor receptor (EGFR) inhibitor that also suppresses lipopolysaccharide (LPS)-induced TNF-α release. This compound is utilized in research areas such as inflammation and oncology, supporting both in vitro cellular studies and in vivo experimental models to investigate EGFR signaling and cytokine regulation.

Research Area

Cardiovascular Research, Signal Transduction

Images & Validation

Key Properties

CAS Number133550-41-1
MW336.38
Purity99.93% (May vary between batches)
FormulaC20H20N2O3
SMILESC(=C(/C(NCCCCC1=CC=CC=C1)=O)\C#N)\C2=CC(O)=C(O)C=C2
TargetEGFR
SolubilityDMSO:50 mg/mL (148.64 mM)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

(E)AG 556, (E)-AG 556, (E) AG 556, (E)-Tyrphostin AG 556, AG556, AG-556, AG 556, inhibit, EGFR, ErbB-1, Epidermal growth factor receptor, Inhibitor, HER1
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Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

(E)-AG 556 (orb1306176)

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Available Sizes

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10 mg
$ 70.00
25 mg
$ 100.00
50 mg
$ 140.00
100 mg
$ 190.00
DispatchUsually dispatched within 3-5 working days
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