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E17110

SKU: orb1987092

Description

E17110 is an LXRβ agonist. E17110 exhibited a significant activation effect on LXRβ (EC50: 0.72 μmol/L). E17110 also increased the expression of ABCA1 and ABCG1 in RAW264.7 macrophages. E17110 significantly decreased cellular lipid accumulation and promoted cholesterol efflux in RAW264.7 macrophages.

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Key Properties

MW334.3
FormulaC16H15FN2O5
SMILESFC1=CC=C2C(OC(C(OC(C(N3C(NCC3)=O)=O)C)=O)=C2C)=C1
TargetOthers

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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Protocol Information

E17110 (orb1987092)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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