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EGFR/VEGFR2-IN-5

SKU: orb2944615

Description

EGFR/VEGFR2-IN-5 (Compound 14) is an orally bioavailable dual inhibitor targeting EGFR (T790M mutant, IC50=0.28 µM) and VEGFR2 (IC50=1.15 µM). It demonstrates potent antitumor efficacy in preclinical studies, supporting its investigation in oncology research for cancers driven by EGFR mutations and angiogenesis.

Research Area

Cardiovascular Research, Cardiovascular Research; Cell Biology, Signal Transduction

Images & Validation

Key Properties

MW429.41
FormulaC17H15N7O5S
TargetEGFR,VEGFR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information