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Elsilimomab Antibody

SKU: orb1980640

Description

Elsilimomab (B-E8) is an anti-interleukin-6 (IL-6) monoclonal antibody. It is utilized in research on multiple myeloma and renal cell carcinoma to study its role in blocking IL-6-mediated signaling, which can inhibit mutant clone-induced stromal senescence in hematopoietic models, as explored in vitro.

Research Area

Immunology & Inflammation

Images & Validation

Key Properties

CAS Number468715-71-1
MW145.96 kDa
Purity98.44% (SEC-HPLC)
TargetInterleukin,IL Receptor

Bioactivity

Target IC50
IL-6:1.4 nM
In Vitro
Elsilimomab is an anti-interleukin-6 (IL-6) IgG1 monoclonal antibody, with a KD of 22 pmol/L and an IC50 of 1.4 nM.

Storage & Handling

StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Anti-Human IL6 Recombinant Antibody, Anti-IL-6 MAB B-E8, BE8, B-E8

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Elsilimomab Antibody (orb1980640)

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% DMSO +
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Available Sizes

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1 mg
$ 230.00
5 mg
$ 670.00
10 mg
$ 1,040.00
25 mg
$ 1,510.00
DispatchUsually dispatched within 5-10 working days
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