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Escin IIA

SKU: orb1684787

Description

Escin IIA, a saponin from horse chestnut seeds, exhibits anti-inflammatory and gastroprotective properties. It reduces ethanol-induced gastric lesions in rat models and is used in preclinical research to study inflammation and mucosal protection mechanisms in both in vivo and in vitro experimental systems.

Research Area

Immunology & Inflammation

Images & Validation

Key Properties

CAS Number158732-55-9
MW1101.24
Purity97.63%
FormulaC54H84O23
SMILES[H][C@@]12CC(C)(C)[C@@H](OC(=O)C(\C)=C\C)[C@H](OC(C)=O)[C@]1(CO)[C@H](O)C[C@]1(C)C2=CC[C@]2([H])[C@@]3(C)CC[C@H](O[C@@H]4O[C@@H]([C@@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](O)[C@H]4O[C@@H]4OC[C@@H](O)[C@H](O)[C@H]4O)C(O)=O)[C@](C)(CO)[C@]3([H])CC[C@@]12C
TargetImmunology/Inflammation related

Bioactivity

In Vivo
Escin IIA (10-50 mg/kg, p.o.) can effectively inhibit ethanol-induced gastric mucosal injury in rats.

Storage & Handling

Storagekeep away from direct sunlight,keep away from moisture,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Aescin IIA
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Key Properties

No computed properties available.

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Protocol Information

Escin IIA (orb1684787)

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Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

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% DMSO +
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% Tween 80 +
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Available Sizes

Select a size below

1 mg
$ 130.00
5 mg
$ 240.00
10 mg
$ 330.00
25 mg
$ 530.00
50 mg
$ 760.00
100 mg
$ 1,030.00
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