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ETTAC-2

SKU: orb2942757

Description

ETTAC-2 is an LRG1-targeting PROTAC degrader (DC50 = 8.38 µM) that inhibits TGF-β/Smad3 signaling. It reduces pro-fibrotic protein secretion and has been shown in research to slow renal fibrosis progression in experimental models, making it a tool for studying fibrotic diseases.

Research Area

Pharmacology & Drug Discovery, Stem Cell & Developmental Biology

Images & Validation

Key Properties

TargetPROTACs,TGF-beta/Smad
Molecular Weight1891.07

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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ETTAC-2 (orb2942757)

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