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F092

SKU: orb1739750

Description

F092 is a potent and selective inhibitor of hematopoietic prostaglandin D synthase (H-PGDS). This small molecule is a valuable research tool for investigating the role of PGD2 in allergic inflammation and vascular disorders, applicable in both cellular assays and animal disease models.

Research Area

Immunology & Inflammation

Images & Validation

Key Properties

CAS Number2250261-59-5
MW359.38
Purity99.63% (May vary between batches)
FormulaC20H17N5O2
SMILESO=C(NC1=CC=C(C=C1)N2C(=O)CCC2)C=3C=NC(=NC3)C4=NC=CC=C4
TargetPGE Synthase
SolubilityDMSO:100 mg/mL (278.26 mM)

Bioactivity

Target IC50
HPGDS:0.14 nM (Kd)

Storage & Handling

Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

F092 inhibitor, GS 5734, GS5734, GS-5734, hPGDS, PGESynthase, PGE Synthase
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

F092 (orb1739750)

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% DMSO +
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% Tween 80 +
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Available Sizes

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1 mg
$ 90.00
5 mg
$ 170.00
10 mg
$ 230.00
25 mg
$ 420.00
50 mg
$ 640.00
100 mg
$ 990.00
200 mg
$ 1,310.00
DispatchUsually dispatched within 6-8 weeks
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