F594-1001 hydrochloride

SKU: orb3134443

Description

F594-1001 hydrochloride (compound 6) is a potent and highly selective inhibitor of SARS-CoV-2 Mac1-ADP-ribose. It exhibits an IC50 of 8.5 μM, 68 μM, and 45 μM in AS, FP, and FRET assays against SARS-CoV-2, respectively. F594-1001 hydrochloride binds directly to SARS-CoV-2 Mac1 and inhibits Mac1 ADP-ribosylhydrolase activity in a dose-dependent manner.

Images & Validation

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Key Properties

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Formula	C₂₃H₂₉Cl₂N₃O₄
Target	SARS-CoV

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

SARS-CoV

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