Felzartamab Antibody

SKU: orb1980441

Description

Felzartamab (MOR-202) is a human monoclonal antibody targeting CD38. It is a research tool for investigating multiple myeloma and advanced antibody-mediated rejection in kidney transplant models. Studies utilize it in both in vitro assays and in vivo preclinical research to explore therapeutic mechanisms.

Research Area

Immunology & Inflammation

Images & Validation

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Key Properties

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CAS Number	2197112-39-1
MW	143.65 kDa
Purity	97.7% (SEC-HPLC)
Target	CD38

Bioactivity

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In Vivo	MOR202 (12 mg/kg; murine MM models) dose-dependently reduced osteolysis by up to 55%. Coadministration with 0.6 mg/kg BOR or 50 mg/kg LEN completely eliminated osteolysis at a low dose of 3 mg/kg. Read more...
In Vitro	MOR202-mediated toxic effects on multiple myeloma (MM) cell lines can be enhanced by the proteasome inhibitor bortezomib (BOR) and the immunomodulator lenalidomide (LEN). Read more...

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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TJ202, TJ-202, TJ 202, CD38, Felzartamab, MOR202, MOR-202, MOR 03087, MOR 202, MOR03087, MOR-03087

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Quick Database Links

Gene Symbol

CD38

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