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Formononetin

SKU: orb1224969

Description

Formononetin is a phytoestrogen from the root of Astragalus membranaceus and an O-methylated isoflavone.

Images & Validation

Key Properties

CAS Number485-72-3
MW268.27
Purity>98% (HPLC)
FormulaC16H12O4
SMILESO=C1C(C2=CC=C(OC)C=C2)=COC3=CC(O)=CC=C13
TargetOthers
SolubilityDMSO: 54 mg/mL (201.29 mM)

Bioactivity

In Vivo
Animal model: BALB/c nude mice bearing MDA-MB-231 xenografts. Dosage: 100 mg/kg. Administration: Treated daily by intragastric administration for 25 days. Result: Inhibited breast cancer growth and angiogenesis In vivo.
In Vitro
Cell Viability Assay Cell line: HUVECs. Concentration: 0, 10, 25, 50, 75, 100, and 150 μM. Incubation time: Result: Significantly decreased the proliferation of HUVECs stimulated by FGF2 in a dose-dependent manner, while had little inhibitory effects on HUVECs that were not stimulated by FGF2.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Biochanin B | NSC 93360

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Formononetin (orb1224969)

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10 mg
$ 90.00
50 mg
$ 100.00
100 mg
$ 130.00
500 mg
$ 250.00