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FXR agonist 3

SKU: orb1982428

Description

FXR agonist 3 is an anti-NASH compound with antifibrotic and anti-fibrotic activity, inhibiting the expression of COL1A1, TGF-β1, α-SMA, and TIMP1, with an IC50 value of 8.19 μmol/L for COL1A1. FXR agonist 3 ameliorates CDAHFD and BDL-induced liver injury in vivo by activating FXR.

Images & Validation

Key Properties

MW521.12
Purity95.04%
FormulaC28H28BrNO4
SMILESCOC1=CC2=C(C=C1OC)CC[N+]3=C2C=C4C(C(OCC5=CC=CC(C)=C5)=C(OC)C=C4)=C3.[Br-]
TargetOthers,FXR

Storage & Handling

Storage-20°C
DisclaimerFor research use only

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FXR agonist 3 (orb1982428)

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1 mg
$ 160.00
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