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FXR agonist 9

SKU: orb2802381

Description

FXR agonist9 (compound 26) is a selective, orally active partial agonist of FXR with an EC50 of 0.09 µM (maximum efficacy of 75.13%). It ameliorates the pathological features of fatty liver disease in mice induced by HFD and CCl4-related metabolic dysfunction.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number2982502-32-7
MW474.55
FormulaC28H30N2O5
SMILESO=C(O)C=1C=CC=C(C1)NC(=O)C=2C=CC=CC2NC(=O)CCCOC3=CC=C(C=C3)C(C)(C)C
TargetFXR

Storage & Handling

Storage-20°C
DisclaimerFor research use only

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FXR agonist 9 (orb2802381)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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