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GAC0001E5

SKU: orb3177761

Description

GAC0001E5 (1E5) is a dual LXR inverse agonist and degrader (IC50 = 5.4-9.1 μM in pancreatic cancer cells). It inhibits tumor growth and induces apoptosis by promoting LXRα/β degradation and suppressing transcriptional activity.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number927969-67-3
MW331.29
Purity98.89% (May vary between batches)
FormulaC17H12F3N3O
SMILESO=C1N=C(NC2=CC=CC(=C2)C(F)(F)F)NC(=C1)C=3C=CC=CC3
TargetLiver X Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

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Protocol Information

Available Sizes

Select a size below

1 mg
$ 140.00
5 mg
$ 280.00
10 mg
$ 420.00
25 mg
$ 670.00
50 mg
$ 930.00
DispatchUsually dispatched within 5-10 working days
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