Galanthamine N-Oxide

SKU: orb1309647

Description

Galanthamine N-Oxide is a natural alkaloid that potently inhibits acetylcholinesterase (AChE) from electric eel with an EC50 of 26.2 µM. It acts as a significant inhibitor of substrate accommodation in the active sites of TcAChE, hAChE, and hBChE, making it a useful research tool for studying cholinesterase function in neurological research.

Research Area

Neuroscience

Images & Validation

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Key Properties

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CAS Number	134332-50-6
MW	303.35
Purity	99.29%
Formula	C₁₇H₂₁NO₄
SMILES	[H][C@]12C[C@@H](O)C=C[C@]11CC[N@@+](C)([O-])Cc3ccc(OC)c(O2)c13
Target	Cholinesterase (ChE)
Solubility	DMSO:55 mg/mL (181.31 mM)

Bioactivity

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Target IC50	AChE:EC50 of 26.2 μM

Storage & Handling

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Storage	Pure form: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Galanthamine N Oxide, Galanthamine NOxide, Galanthamine N-Oxide, Inhibitor, inhibit, Cholinesterase (ChE), AChE, accommodation, alkaloid, active, substrate, site

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Compound Identifiers

PubChem CID

71587486 ↗

Key Properties

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No computed properties available.

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