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Gastrodin

SKU: orb1941025

Description

Gastrodin, an anti-inflammatory polyphenol extracted from Chinese natural herbal Gastrodia elata Blume., benefits neurodegenerative diseases. Extracted from Orchids Gastrodia; Suitability:Water,methanol,ethanol;Store the product in sealed,cool and dry condition.(In Vitro):Gastrodin treatment reduces the mRNA expression levels of TNF-α and iNOS in the retinas of acute ocular hypertension.(In Vivo):Intraperitoneal injection with Gastrodin 10 mg/kg or 50 mg/kg once daily for 15 d significantly inhibits the loss of retinal ganglion cells (RGCs) because of acute ocular hypertension (AOH) damage. 2 wk after AOH, the number of Iba1 positive retinal microglia obviously reduces to 231.3±54.3 cells/mm2 and 201.9±43.1 cells/mm2 in the rats intraperitoneally injected with Gastrodin at 10 mg/kg and 50 mg/kg, respectively.

Images & Validation

Key Properties

CAS Number62499-27-8
MW286.28
Purity>98% (HPLC)
FormulaC13H18O7
SMILESC1=CC(=CC=C1CO)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O
TargetOthers
SolubilityDMSO: 50 mg/mL (174.65 mM)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Gastrodin (orb1941025)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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