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GDC-0623

SKU: orb1300414

Description

GDC-0623

Research Area

Cell Biology, Signal Transduction

Images & Validation

Key Properties

CAS Number1168091-68-6
MW456.21
Purity98.95%
FormulaC16H14FIN4O3
SMILESOCCONC(=O)c1ccc2cncn2c1Nc1ccc(I)cc1F
TargetApoptosis,MEK
SolubilityDMSO:91 mg/mL (199.47 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.23 mM);Ethanol:5 mg/mL (10.96 mM)

Bioactivity

Target IC50
MEK1:0.13 nM(ki)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Apoptosis, G868, G-868, G 868, Inhibitor, GDC 0623, GDC0623, GDC-0623, MEK, MEK inhibitor 1, MEK inhibitor1, MEK inhibitor-1, MEK1, MAPKK, MAP2K, inhibit, Mitogen-activated protein kinase kinase, RG 7421, RG7421, RG-7421

Similar Products

  • GDC-0623 [orb1223413]

    >98% (HPLC)

    1168091-68-6

    456.21

    C16H14FIN4O3

    1 g, 500 mg, 200 mg, 2 mg, 5 mg, 25 mg, 50 mg, 100 mg, 10 mg
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Key Properties

No computed properties available.

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Protocol Information

GDC-0623 (orb1300414)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
$ 90.00
2 mg
$ 110.00
1 ml x 10 mM (in DMSO)
$ 170.00
5 mg
$ 170.00
10 mg
$ 240.00
25 mg
$ 340.00
50 mg
$ 430.00
100 mg
$ 690.00
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