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Ginsenoside Rg5

SKU: orb1222582

Description

Ginsenoside Rg5 could be a beneficial agent for the treatment of Alzheimer's disease. Ginsenoside Rg5 suppresses LPS-induced nitric oxide (NO) production and proinflammatory TNF-α secretion. Ginsenoside Rg5 can ameliorate lung inflammation possibly by inhibiting the binding of LPS to toll-like receptor (TLR)-4 on macrophages. Ginsenoside Rg5 plays a novel role as an IGF-1R agonist, promoting therapeutic angiogenesis and improving hypertension without adverse effects in the vasculature. Ginsenoside Rg5 blocks cell cycle of SK-HEP-1 cells at the Gl/S transition phase by down-regulating cyclin E-dependent kinase activity and that the down-regulation of cyclin E-dependent kinase activity is caused mainly by induced CDK2 inhibitor, p21Cip/WAF1 and decreased levels of cyclin E.

Images & Validation

Key Properties

CAS Number186763-78-0
MW767.01
Purity>98% (HPLC)
FormulaC42H70O12
SMILESCC(=CCC=C(C)C1CCC2(C1C(CC3C2(CCC4C3(CCC(C4(C)C)OC5C(C(C(C(O5)CO)O)O)OC6C(C(C(C(O6)CO)O)O)O)C)C)O)C)C
TargetIGF-1R
SolubilityIn Vitro: DMSO : 50 mg/mL (65.19 mM)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Ginsenoside Rg5 (orb1222582)

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200 mg
500 mg
5 mg
$ 390.00
10 mg
$ 610.00
25 mg
$ 970.00
50 mg
$ 1,290.00
100 mg
$ 1,800.00