Glucocorticoid receptor agonist-1

SKU: orb1692476

Description

Glucocorticoid receptor agonist-1 is a high-affinity synthetic ligand for the GR, exhibiting potent agonist activity with an IC50 of 2.8 nM. It is a valuable research tool for studying glucocorticoid receptor signaling and its roles in inflammation, metabolism, and stress response in both cellular and animal models.

Research Area

Metabolism Research

Images & Validation

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Key Properties

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CAS Number	2166375-82-0
MW	569.69
Purity	99.68%
Formula	C₃₅H₃₉NO₆
SMILES	[H][C@]1(O[C@]2([H])C[C@@]3([H])[C@]4([H])CCC5=CC(=O)C=C[C@]5(C)[C@@]4([H])[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO)c1ccc(Cc2cccc(N)c2)cc1
Target	ADC Cytotoxin,Glucocorticoid Receptor
Solubility	DMSO:50 mg/mL (87.77 mM);10% DMSO+90% Corn Oil:2.5 mg/mL (4.39 mM)

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Disclaimer	For research use only

Alternative Names

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ADC Cytotoxin, ADCCytotoxin, Glucocorticoid Receptor, Glucocorticoid receptor agonist 1, Glucocorticoid receptor agonist1, Glucocorticoid receptor agonist-1, GlucocorticoidReceptor

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Compound Identifiers

PubChem CID

134491939 ↗

Key Properties

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No computed properties available.

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