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Glucocorticoid receptor/NF-κB modulator-1

SKU: orb3134161

Description

Glucocorticoid receptor/NF-κB modulator-1 (Compound 20) is a derivative of ocotillol. It prevents degradation of glucocorticoid receptor (GR) mRNA and GR protein and inhibits the activation of the NF-κB signaling pathway. Additionally, it reduces levels of nitric oxide (NO), interleukin (IL-6), and tumor necrosis factor-alpha (TNF-α), and improves sepsis in mice.

Images & Validation

Key Properties

FormulaC39H62N2O6S
TargetNF-κB,Glucocorticoid Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information

Glucocorticoid receptor/NF-κB modulator-1 (orb3134161)

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