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GNF-351

SKU: orb746446

Description

GNF-351 is a potent, pure aryl hydrocarbon receptor (AHR) antagonist (IC50=62 nM) devoid of partial agonist potential; antagonizes agonist and SAhRM-mediated suppression of SAA1, inhibit both DRE-dependent and -independent activity; decreases migration and invasion of HNSCC cells and prevents benzo[a]pyrene-mediated induction of the chemotherapy efflux protein ABCG2.

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Key Properties

MW411.5
Purity>98%
FormulaC24H25N7
SMILESN1C2C(=NC(C3=CC(C)=CN=C3)=NC=2NCCC2C3=C(N=C2)C=CC=C3)N(C(C)C)C1

Storage & Handling

DisclaimerFor research use only
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GNF-351 (orb746446)

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100 mg
$ 700.00
250 mg
$ 1,140.00
1 g
$ 2,250.00
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