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Graveoline

SKU: orb1297035

Description

Graveoline is a small molecule research compound that functions as an inducer of both apoptosis and autophagy. It has been investigated in in vitro studies for its effects on skin melanoma cell lines, highlighting its potential utility in cancer research and cell death mechanism studies.

Research Area

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Infectious Disease & Virology, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number485-61-0
MW279.29
Purity98.14%
FormulaC17H13NO3
SMILESCn1c(cc(=O)c2ccccc12)-c1ccc2OCOc2c1
TargetAutophagy,Interleukin,Parasite,ROS,Antifungal,JAK,STAT,Apoptosis
SolubilityDMSO:5.2 mg/mL (18.62 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.58 mM)

Bioactivity

In Vitro
Results of MTT assay revealed that, in case of A375 cells,the cell viability gradually decreased upon administration of minimal concentration to the higher ones of graveoline. Upon treatment with 22.23 ± 0.79 μg/mL of graveoline,the cell viability reduced to 50% .

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

autophagy, 2-(Benzo[d][1,3]dioxol-5-yl)-1-methylquinolin-4(1H)-one, Foliosine, Graveoline

Similar Products

  • Graveoline [orb1217987]

    >98% (HPLC)

    485-61-0

    279.29

    C17H13NO3

    1 g, 500 mg, 200 mg, 100 mg, 5 mg
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Key Properties

No computed properties available.

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Protocol Information

Graveoline (orb1297035)

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Available Sizes

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1 ml x 10 mM (in DMSO)
$ 70.00
50 mg
$ 190.00
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