Grp94 Inhibitor-1

SKU: orb1299961

Description

Grp94 Inhibitor-1 is a highly potent and selective small molecule targeting Grp94 with a 2 nM IC50. This research compound is utilized in vitro and in vivo to study endoplasmic reticulum stress, protein folding, and related pathologies such as cancer and inflammatory diseases.

Research Area

Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

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Key Properties

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CAS Number	2234897-35-7
MW	352.47
Purity	98.00% (May vary between batches)
Formula	C₂₂H₂₈N₂O₂
SMILES	CC(C)c1ccc(cc1)-c1ccc(N[C@H]2CC[C@H](O)CC2)c(c1)C(N)=O
Target	GPCR,HSP
Solubility	10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.67 mM);DMSO:25 mg/mL (70.93 mM)

Bioactivity

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Target IC50	Grp94:2 nM

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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inhibit, Inhibitor, Heat shock proteins, integrin α2, integrin αL, Grp94, Grp94 Inhibitor 1, Grp94 Inhibitor1, Grp-94 Inhibitor-1, Grp94 Inhibitor-1, HSP

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Compound Identifiers

PubChem CID

137321151 ↗

Key Properties

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No computed properties available.

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