Cart summary

You have no items in your shopping cart.

GSK547

SKU: orb1299856

Description

GSK547 is a potent and selective RIP1 kinase inhibitor. It has been shown to block macrophage-induced adaptive immune tolerance in pancreatic cancer models, supporting its use in oncology and immunology research involving both in vitro and in vivo studies.

Research Area

Cell Biology, Signal Transduction

Images & Validation

Key Properties

CAS Number2226735-55-1
MW396.39
Purity99.17% (May vary between batches)
FormulaC20H18F2N6O
SMILESFc1cc(F)cc(c1)[C@@H]1CC=NN1C(=O)C1CCN(CC1)c1cc(ncn1)C#N
TargetRIP kinase
SolubilityDMSO:125 mg/mL (315.35 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.09 mM)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Inhibitor, inhibit, GSK 547, GSK547, GSK'547, GSK-547, Receptor-interacting protein kinases, RIP kinase, RIP1, RIPK, RIPkinase

Similar Products

  • GSK547 [orb1225622]

    >98% (HPLC)

    2226735-55-1

    396.402

    C20H18F2N6O

    100 mg, 1 g, 500 mg, 200 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Key Properties

No computed properties available.

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

GSK547 (orb1299856)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

2 mg
$ 80.00
1 ml x 10 mM (in DMSO)
$ 100.00
5 mg
$ 100.00
10 mg
$ 140.00
25 mg
$ 220.00
50 mg
$ 320.00
100 mg
$ 420.00
DispatchUsually dispatched within 3-5 working days
Bulk Enquiry