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Gymnestrogenin

SKU: orb1684554

Description

Gymnestrogenin is a natural triterpenoid that functions as a liver X receptor (LXR) antagonist. This bioactive compound is utilized in biochemical research for studying lipid metabolism and inflammation, with applications in both in vitro and in vivo experimental models.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number19942-02-0
MW490.72
Purity99.97%
FormulaC30H50O5
SMILESC(O)[C@]12[C@](C=3[C@@](C)(C[C@@H]1O)[C@@]4(C)[C@](CC3)([C@]5(C)[C@@](CC4)([C@@](CO)(C)[C@@H](O)CC5)[H])[H])(CC(C)(C)[C@@H](O)C2)[H]
TargetLiver X Receptor
SolubilityDMSO:≥ 40 mg/mL

Bioactivity

Target IC50
LXRβ:1.4 μM|LXRα:2.5 μM
In Vitro
In HepG2 cells, Gymnestrogenin exhibited dual antagonistic effects on liver X receptor α (LXRα) and β (LXRβ), with IC50 values of 2.5 μM and 1.4 μM, respectively .

Storage & Handling

Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Gymnestrogenin, LiverXReceptor, Liver X Receptor
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Key Properties

No computed properties available.

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Protocol Information

Gymnestrogenin (orb1684554)

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% DMSO +
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% Tween 80 +
%

Available Sizes

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1 mg
$ 170.00
5 mg
$ 340.00
10 mg
$ 480.00
25 mg
$ 770.00
50 mg
$ 1,030.00
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