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Hamaudol

SKU: orb1297346

Description

Hamaudol

Research Area

Immunology & Inflammation, Neuroscience

Images & Validation

Key Properties

CAS Number735-46-6
MW276.28
Purity99.62%
FormulaC15H16O5
SMILESCc1cc(=O)c2c(O)c3C[C@H](O)C(C)(C)Oc3cc2o1
TargetCOX
SolubilityDMSO:< 10 mM

Bioactivity

Target IC50
COX-2:57 mM |COX-1:0.30 mM
In Vitro
The CHCl3 extract of the root of Angelica japonica showed high inhibitory activity against human gastric adenocarcinoma (MK-1) cell growth. From this extract, a new furanocoumarin named japoangelone and four furanocoumarin ethers of falcarindiol, named japoangelols A-D, were isolated together with caffeic acid methyl ester, four polyacetylenic compounds (panaxynol, falcarindiol, 8-O-acetylfalcarindiol, and (9Z)-1,9-heptadecadiene-4,6-diyne-3,8,11-triol), eight coumarins (osthol, isoimperatorin, scopoletin, byakangelicin, xanthotoxin, bergapten, oxypeucedanin methanolate, and oxypeucedanin hydrate), and two chromones (3'-O-acetylHamaudol, and Hamaudol)

Storage & Handling

Storagekeep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

COX, COX-2, COX-1, Cyclooxygenase, Inhibitor, inhibit, Hamaudol

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Key Properties

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Hamaudol (orb1297346)

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1 mg
$ 140.00
5 mg
$ 280.00