Harmine hydrochloride

SKU: orb1304990

Description

Harmine hydrochloride, also known as telepathine hydrochloride, is a natural alkaloid isolated from plants of the Peganum harmala genus. This compound is widely used in biochemical research as a potent and selective inhibitor of monoamine oxidase A (MAO-A) and has been investigated in vitro and in vivo for its effects on neurobiology and cell proliferation.

Research Area

Cell Biology, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

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Key Properties

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CAS Number	343-27-1
MW	248.71
Purity	>99.99% (May vary between batches)
Formula	C₁₃H₁₃ClN₂O
SMILES	Cl.COc1ccc2c(c1)[nH]c1c(C)nccc21
Target	5-HT Receptor,GluR,DYRK
Solubility	DMSO:2 mg/mL (8.04 mM)

Bioactivity

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Target IC50	MNB:149 nM\|DYRK1A:33 nM\|DYRK2:1.9 μM\|DYRK1B:166 nM\|5-HT2A receptor:397 nM (Ki)

Storage & Handling

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Storage	keep away from moisture,keep away from direct sunlight \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Inhibitor, GluR1, Harmine, Harmine hydrochloride, Harmine Hydrochloride, inhibit, 5-hydroxytryptamine Receptor, 5HTReceptor, 5-HT Receptor, 5HT Receptor, Dual specificity tyrosine phosphorylation regulated kinase, Dual specificity tyrosine regulated kinase, DYRK1B, DYRK, DYRK2, DYRK1A, Telepathine, telepathine hydrochloride, telepathine Hydrochloride, Serotonin Receptor

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Compound Identifiers

PubChem CID

5359389 ↗

Key Properties

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No computed properties available.

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