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HM03

SKU: orb1298729

Description

HM03 is a small molecule research compound that selectively inhibits the chaperone protein HSPA5 (GRP78). This inhibition has demonstrated anticancer activity in cellular studies, making it a useful tool for investigating endoplasmic reticulum stress pathways in oncology research.

Research Area

Metabolism Research, Signal Transduction

Images & Validation

Key Properties

CAS Number500565-15-1
MW462.97
Purity97.15%
FormulaC26H27ClN4O2
SMILESCOc1ccc2nc3cc(Cl)ccc3c(Nc3ccc(O)c(CN4CCN(C)CC4)c3)c2c1
TargetHSP
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.8 mM);DMSO:125 mg/mL (270 mM)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

cancer, cell, inhibit, Inhibitor, Heat shock proteins, heat, HCT116, HM-03, HM03, HM 03, HSPA5, HSP, tumor, protein, shock

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Key Properties

No computed properties available.

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Protocol Information

HM03 (orb1298729)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

5 mg
$ 80.00
1 ml x 10 mM (in DMSO)
$ 90.00
10 mg
$ 110.00
25 mg
$ 170.00
50 mg
$ 260.00
100 mg
$ 390.00
200 mg
$ 560.00
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