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HNC-1664

SKU: orb2944939

Description

HNC-1664 is an orally active inhibitor of RNA-dependent RNA polymerase (RdRP). It exhibits broad-spectrum antiviral activity against coronaviruses, including SARS-CoV-2 wild type and its variants (XBB.1.18, HK.3.1, BF.7.14, BA.1, HCoV-229E, HCoV-OC43), as well as arenaviruses. HNC-1664 also demonstrates anti-infective efficacy in a mouse model infected with the SARS-CoV-2 Delta variant.

Research Area

Cell Biology, Infectious Disease & Virology, Molecular Biology

Images & Validation

Key Properties

CAS Number2127358-36-3
MW393.153
FormulaC12H13FIN3O3
SMILESF[C@@H]1[C@H](N2C=3C(C(I)=C2)=C(C)N=CN3)O[C@H](CO)[C@H]1O
TargetSARS-CoV,Virus Protease,Anti-infection,DNA/RNA Synthesis

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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HNC-1664 (orb2944939)

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