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HPK1-IN-56

SKU: orb2945330

Description

HPK1-IN-56 (Compound A29) is a potent HPK1 inhibitor with single-digit nM IC50 values in biochemical and cellular assays. It promotes IL-2 production in human PBMCs and enhances T-cell function, supporting research into its potential to improve anticancer immunotherapies, such as in combination with anti-PD-1 antibodies.

Research Area

Immunology & Inflammation, Signal Transduction

Images & Validation

Key Properties

CAS Number2901054-39-3
MW442.516
FormulaC24H26N8O
SMILESN1=NC=2C(N=C1NC=3C=C4C(=CC3OC)CCN(C)C4)=CC(=CC2N)C=5C=NC=C(N)C5C
TargetInterleukin,MAPK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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HPK1-IN-56 (orb2945330)

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