Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

HsClpP activator-2

SKU: orb3173256

Description

HsClpP activator-2 is an orally active HsClpP agonist with a KD of 40 nM. It exhibits significant inhibitory effects on small cell lung cancer (SCLC) cells, including H69 (IC50 = 0.17 μM) and H82 (IC50 = 0.19 μM). This compound disrupts mitochondrial membrane potential (MMP), induces apoptosis (apoptosis), and promotes ROS production in H82 cells. Additionally, HsClpP activator-2 significantly suppresses tumor growth in non-SMC cell xenograft models and is applicable for research in small cell lung cancer (SCLC).

Research Area

Cell Biology, Immunology & Inflammation, Protein Biochemistry

Images & Validation

−
HsClpP activator-2

Key Properties

−
TargetProtease,ROS,Apoptosis

Storage & Handling

−
Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Similar Products

−
  • ClpP activator-2

    ClpP activator-2 [orb3211413]

    3036751-71-7

    483.31

    C22H19Cl2F3N4O

    50 mg, 10 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Quick Database Links

Gene Symbol
Protease,ROS,Apoptosis

Protocol Information

Find More Protocols

Available Sizes

Select a size below

10 mg
Enquire
50 mg
Enquire
Bulk Enquiry
Need technical support? Find your Distributor Return and Tax Policy

Email

info@biorbyt.com

UK Office

+44 (0)1223 859353

US Office

+1 (415) 906-5211

CN Office

+86 (27)-87663101

Distributors

biorbyt.com/distributor