Human beta-Galactosidase-1 Protein, His Tag

SKU: orb1786143

Description

This gene encodes a member of the glycosyl hydrolase 35 family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature lysosomal enzyme. This enzyme catalyzes the hydrolysis of a terminal beta-linked galactose residue from ganglioside substrates and other glycoconjugates. Mutations in this gene may result in GM1-gangliosidosis and Morquio B syndrome. [provided by RefSeq, Nov 2015]

Images & Validation

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Application Notes	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 75.5 kDa. The protein migrates as 80-95 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Key Properties

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Source	Human beta-Galactosidase-1 Protein, His Tag (orb1786143) is expressed from human 293 cells (HEK293). It contains AA Leu 24 - Val 677 (Accession # P16278-1).
Expression System	HEK293
Target	beta-Galactosidase-1
Reactivity	Human
Tag	C-10×His
Molecular Weight	75.5 kDa
Expression Region	Leu 24 - Val 677
Purity	95%
Endotoxins	1.0 EU per μg
Conjugation	Unconjugated

Storage & Handling

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Storage	-20°C
Form/Appearance	Powder
Buffer/Preservatives	50 mM Tris, 150 mM NaCl, 20% Glycerol, pH 7.5
Expiration Date	6 months from date of receipt.
Dry Ice Shipping	Please note: This product requires shipment on dry ice. A dry ice surcharge will apply.
Disclaimer	For research use only

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Quick Database Links

Gene Symbol

beta-Galactosidase-1

UniProt

P16278

RefSeq:P16278

UniProt Details

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No UniProt data available

NCBI Reference Sequences

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Associated Accession Numbers

Curated reference sequences for the gene transcript and protein product

RefSeq	P16278

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