Human CD39L1 / ENTPD2 Protein, His Tag (active enzyme, MALS verified)

SKU: orb1733263

Description

CD39L1, also known as ENTPD2 and NTPDase2, is an ectonucleotidase belonging to the CD39 family. It is found on the surface of vascular adventitial cells and accessory vascular cells . CD39L1 is a Ca2+ and Mg2+ dependent enzyme that hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent. The order of activity with different substrates is ATP > GTP > CTP = ITP > UTP > > ADP = UDP. CD39L1 plays a role in regulating thrombosis and inflammation . It is considered to be a therapeutic target for thromboregulation and the treatment of vascular inflammation.

Images & Validation

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Application Notes	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 49.0 kDa. The protein migrates as 36-37 kDa and 57-63 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Key Properties

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Source	Human CD39L1/ENTPD2 Protein, His Tag (orb1733263) is expressed from CHO cells. It contains AA Thr 29 - Asp 460 (Accession # Q9Y5L3-1).
Expression System	CHO
Target	CD39L1/ENTPD2
Reactivity	Human
Tag	C-10×His
Molecular Weight	49.0 kDa
Expression Region	Thr 29 - Asp 460
Purity	95%
Endotoxins	1.0 EU per μg
Conjugation	Unconjugated

Storage & Handling

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Storage	-70℃
Form/Appearance	Liquid
Buffer/Preservatives	20 mM Tris, 150 mM NaCl, pH7.5
Expiration Date	6 months from date of receipt.
Dry Ice Shipping	Please note: This product requires shipment on dry ice. A dry ice surcharge will apply.
Disclaimer	For research use only

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Quick Database Links

Gene Symbol

CD39L1/ENTPD2

UniProt

Q9Y5L3

RefSeq:Q9Y5L3

UniProt Details

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No UniProt data available

NCBI Reference Sequences

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Associated Accession Numbers

Curated reference sequences for the gene transcript and protein product

RefSeq	Q9Y5L3

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