Human FASN Protein, His Tag (active enzyme)

SKU: orb3158051

Description

The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. [provided by RefSeq, Jul 2008]

Images & Validation

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Application Notes	This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 58.3 kDa. The protein migrates as 34-39 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).

Key Properties

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Expression System	E. coli
Target	FASN
Reactivity	Human
Tag	N-10×His
Molecular Weight	58.3 kDa
Expression Region	Leu 2200 - Gly 2511
Purity	95%
Conjugation	Unconjugated

Storage & Handling

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Storage	-70°C
Form/Appearance	Liquid
Buffer/Preservatives	20 mM Tris, 500 mM NaCl, pH 7.9
Expiration Date	6 months from date of receipt.
Dry Ice Shipping	Please note: This product requires shipment on dry ice. A dry ice surcharge will apply.
Disclaimer	For research use only

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Quick Database Links

Gene Symbol

FASN

UniProt

NP_004095-1

RefSeq (Protein):NP_004095

UniProt Details

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No UniProt data available

NCBI Reference Sequences

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Associated Accession Numbers

Curated reference sequences for the gene transcript and protein product

Protein	NP_004095

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